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This study was undertaken to evaluate the effect of the expression level of thymidylate synthase (TS) gene in colon carcinoma tissue on the response to 5-fluorouracil (5-FU) therapy. METHODS AND MATERIALS: Surgically resected specimens from 93 patients with stage II or III colon carcinoma were examined for the expression of TS gene by reverse transcription polymerase chain reaction analysis. The pathological response to 5-FU therapy was evaluated by postoperative examination of tumor tissues. Tumors with a reduction rate of the TS mRNA expression in 5-FU-treated samples of > or = 30% were defined as having a good response. The frequency of the good response in the TS-high expression group was significantly higher than that in the TS-low expression group, with a difference in the survival of patients of 28 months. TS expression level in colon carcinoma tissue may be used to predict the response to 5-FU therapy.Field of the Invention
The present invention relates to an operation portion of a touch panel.
Description of the Background Art
There is a known touch panel mounted on a display such as a liquid crystal display device. For example, such a touch

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2015-10-17 By Marilena Prisciano

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